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This article documents Best Practices, Limitations, and Considerations relating to the use of storage that has Microsoft Windows Deduplication enabled when storing backup files created and managed by Veeam Backup & Replication.
[CRITICAL] Veeam strongly recommends that all Microsoft Data Deduplication tasks be scheduled to operate when Veeam jobs are not operating, as Microsoft Data Deduplication tasks can and will interfere with Veeam backup file creation and manipulation operations. Microsoft recommends that "Optimally, Data Deduplication should have 1 GB of memory for every 1 TB of logical data. For instance, if you are optimizing a 10 TB volume, you would optimally need 10 GB of memory allocated for Data Deduplication (1 GB * 10). This ratio will ensure the maximum performance for Data Deduplication jobs." Data Deduplication on ReFS requires at least Server 2019. Veeam recommends that the MinimumFileSize value be set to prevent Microsoft Data Deduplication from causing file locks on smaller metadata (vbm,vacm,vasm) files associated with restore point creation. PowerShell example command:Adjust volume letter as needed.
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