OPERATIONAL DEFECT DATABASE
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Jobs of any type fail with the error, “Application is shutting down.” For example:
The Veeam Backup Service uses a system of timed leases to monitor the many processes it manages. Usually, this error involves a five minute lease for the VeeamAgent processes (Data Movers). When the Veeam Backup Service is operating normally, this lease is continually renewed. If the lease expires, the associated process is shut down. Typically the lease will expire either because the system time has changed by several minutes, or because a problem communicating with the Veeam Backup Configuration Database has prevented the Veeam Backup Service from renewing the lease.
On VMware virtual machines, VMware Tools will periodically synchronize the system time with the ESXi host. If the time on the host differs from the NTP server used by the Guest OS, the system time will repeatedly shift between the two different times. The best solution is to synchronize the time between the ESXi host and the Veeam Backup Server and/or the domain controllers with the same source. If this is not possible, you could disable VMware Tools time synchronization on the Veeam Backup Server. If time synchronization is not the problem, please create a Veeam Support Case.
VMware KB: Timekeeping best practices for Windows, including NTP
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