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When operating a Windows-based vCenter, if the VM running Microsoft SQL that is hosting that vCenter's database (VCDB) is processed by a backup job with Application-Aware Processing enabled, the VSS freeze operation that occurs during Application-Aware Processing will freeze the vCenter database. This database freeze will cause Application-Aware Processing to fail as the vCenter's frozen database cannot process the ESXi host's snapshot creation response.
By default, Veeam Backup & Replication will attempt to identify and automatically exclude the VCDB (default name of the vCenter Database) from the VSS freeze operation, however, the database detection automatic exclusion may not work correctly when the VCDB is hosted on a separate machine from the Windows-based vCenter VM. To resolve this, enable the Database Exclusion menu option and configure a database exclusion. How to Exclude Microsoft SQL Databases from Application-Aware Processing
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