The earliest recollection of this bug is traced back to PAN-OS 8.1.16 - January 09, 2024.
This bug is fixed in PAN-OS versions 9.1.5, 8.1.16.
Fixed an issue on Panorama where the web interface took more time than expected to load changes when the virtual router was large or when there was a large configuration change request from the web interface.
For more information:
https://docs.paloaltonetworks.com/pan-os/8-1/pan-os-release-notes/pan-os-8-1-addressed-issues/pan-os-8-1-16-addressed-issues
https://docs.paloaltonetworks.com/pan-os/9-1/pan-os-release-notes/pan-os-9-1-addressed-issues/pan-os-9-1-5-addressed-issues