Symptom
This DOC request is to add a note that since TCP intercept and Application inspection are not performed it is essential that all traffic flow through the same FTD device for the IPS to operate correctly to prevent intrusions.
Inline Sets and Passive Interfaces for Firepower Threat Defense
https://www.cisco.com/c/en/us/td/docs/security/firepower/630/configuration/guide/fpmc-config-guide-v63/inline_sets_and_passive_interfaces_for_firepower_threat_defense.html#reference_62C2A6976E334458AC1982083304A226