Symptom
Cisco.com Nexus 9000 Series NX-OS Interfaces Configuration Guide states that "The static NAT feature over vPC is not supported on Cisco Nexus 9300 platform switches". The reason for this restriction is not given.
The Dynamic NAT may or may not work with vPC depending whether out-in and in-out traffic takes the same path. The documentation is missing the restriction on using the Dynamic NAT with vPC.
Conditions
Static NAT configured on SVIs for vPC VLANs.